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Our vision:
Miniaturized components dominating future healthcare infrastructure Shifting healthcare from the hospital to bio-integrated systems, which is an urgent need when the medical resources are limited, requires new interfaces that can conformally accommodate biological motions, accurately elucidate the spatial and temporal dynamics of biochemical signals in real time, and precisely deliver treatment based on the information matrix on demand. Our research addresses these challenges by integrating knowledges from new materials, advanced fabrication, and analytical chemistry to build an ecosystem consisting of soft, small, and smart sensors and robots that can operate within living systems for precision diagnosis and treatment. |
Bio robotics
Micro & nanoscale robots
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"Small machines might be permanently incorporated in the body to assist some inadequately-functioning organ." Richard Feynman
References: Micro/Nanorobots for Biomedicine: Delivery, Surgery, Sensing, and Detoxification Science Robotics 2017 Biomimetic Platelet‐Camouflaged Nanorobots for Binding and Isolation of Biological Threats Adv. Mater. 2018 Micromotor-Enabled Active Drug Delivery for In Vivo Treatment of Stomach Infection. Nature Commun. 2017 Enteric Micromotor Can Selectively Position and Spontaneously Propel in the Gastrointestinal Tract ACS Nano 2016 |
Soft robots
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"Nature uses soft materials frequently and stiff materials sparingly." Steven Vogel
References: Electronic Skins and Machine Learning for Intelligent Soft Robots Science Robotics 2020 J. Li, V. Mottini, Z. Bao et al, A Transformation Intelligence Elastomer (TIE) Soft Robot. under review. |
Biosensors and neuroelectronics
Neurotransmitter sensors
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"The human brain is the most complicated organization of matter that we know."
Isaac Asimov References: J. Li, Y. Liu, X. Chen, Z. Bao et al, NeuroString: a tissue-like neurotransmitter sensor for interfacing with brain and gut. in press. |
Adaptive electronics
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"Children are not little adults - they need medicine sensitive to the changes in their biology as they grow." Stanford Medical School
References: Morphing Electronics for Growing Tissue Nature Biotechnology 2020. |